ELAV-Like Protein 1
An RRM protein that binds to the 3'-UTR region of mRNAs and increases their stability. In EMBRYONIC STEM CELLS, it binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs and preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), to stabilize them and promote differentiation.
Year introduced: 2016
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Subheadings:
Tree Number(s): D12.776.157.725.813.500.250, D12.776.664.962.813.500.250
MeSH Unique ID: D000067780
Entry Terms:
- ELAV Like Protein 1
- ELAVL1 protein
- protein, ELAVL1
- HuR Paraneoplastic Encephalomyelitis Antigen
- HuR Antigen
- Antigen, HuR
- HuR Protein
- Protein, HuR
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