Aripiprazole

A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.

Year introduced: 2016 (1995)

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D03.383.606.170, D03.633.100.810.835.122

MeSH Unique ID: D000068180

Registry Number: 82VFR53I78

Entry Terms:

• Aripiprazol
• 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone
• OPC 14597
• OPC-14597
• Abilify

Pharmacologic Action:

• Antidepressive Agents
• Antipsychotic Agents
• Dopamine Agonists
• Serotonin 5-HT1 Receptor Agonists
• Serotonin 5-HT2 Receptor Antagonists
• Dopamine D2 Receptor Antagonists

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Piperazines
Aripiprazole

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, Fused-Ring
Heterocyclic Compounds, 2-Ring
Quinolines
Quinolones
Aripiprazole