Omalizumab
An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA.
Year introduced: 2016 (2001)
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Tree Number(s): D12.776.124.486.485.114.071.500, D12.776.124.486.485.114.224.060.844, D12.776.124.790.651.114.071.500, D12.776.124.790.651.114.224.060.844, D12.776.377.715.548.114.071.500, D12.776.377.715.548.114.224.200.844
MeSH Unique ID: D000069444
Registry Number: 2P471X1Z11
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