Discoidin Domain Receptors
Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX.
Year introduced: 2017 (1999)
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Subheadings:
Tree Number(s): D08.811.913.696.620.682.725.400.005, D12.776.476.568.400.005, D12.776.543.750.630.005, D12.776.543.750.685.050, D12.776.543.750.705.880.300
MeSH Unique ID: D000070818
Registry Number: EC 2.7.10.1
Entry Terms:
- Receptors, Discoidin Domain
- Discoidin Domain Receptor
- Receptor, Discoidin Domain
- DDR Proteins
- Proteins, DDR