U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tensins

A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.

Year introduced: 2017 (1992)

PubMed search builder options

Subheadings:

Tree Number(s): D05.750.078.730.719, D12.776.220.525.719

MeSH Unique ID: D000070876

Entry Terms:

  • Tensin

Supplemental Content

Loading ...