ADAMTS5 Protein
An ADAMTS protease that contains two C-terminal thrombospondin (TS) motifs. It functions primarily as an aggrecanase, cleaving AGGRECAN in CARTILAGE, and may be involved in the destruction of aggrecan in ARTHRITIS.
Year introduced: 2017
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Subheadings:
Tree Number(s): D08.811.277.656.675.374.102.500.875, D09.400.430.500.500.875, D12.776.395.033.500.875, D12.776.860.300.085.875
MeSH Unique ID: D000071116
Registry Number: EC 3.4.24.-
Entry Terms:
- ADAMTS-5 Protein
- ADAMTS 5 Protein
- ADAMTS5 Protease
- ADAMTS11 Protein
- Aggrecanase-2
- Aggrecanase 2
- A Disintegrin And Metalloproteinase With Thrombospondin Motifs 5 Protein
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