ADAMTS4 Protein
An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may also be involved in the destruction of aggrecan in ARTHRITIS.
Year introduced: 2017 (1999)
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Subheadings:
Tree Number(s): D08.811.277.656.675.374.102.500.844, D09.400.430.500.500.844, D12.776.395.033.500.844, D12.776.860.300.085.844
MeSH Unique ID: D000071121
Registry Number: EC 3.4.24.82
Entry Terms:
- ADAMTS-4 Protein
- ADAMTS 4 Protein
- Aggrecanase-1
- Aggrecanase 1
- A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein