Promyelocytic Leukemia Protein
A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.
Year introduced: 2017
PubMed search builder options
Subheadings:
Tree Number(s): D12.776.624.776.654, D12.776.660.745, D12.776.930.713, D12.776.934.500
MeSH Unique ID: D000071156
Entry Terms:
- TRIM19 Protein
- RNF71 Protein
Previous Indexing: