Proprotein Convertase 9
A proprotein convertase that is essential for CHOLESTEROL homeostasis. It binds to and is required for the lysosomal degradation of the LDL RECEPTOR (LDLR); the VLDL receptor, and the APOLIPOPROTEIN E RECEPTOR. It also regulates neuronal APOPTOSIS.
Year introduced: 2017
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Subheadings:
Tree Number(s): D08.811.277.656.300.760.718, D08.811.277.656.837.688, D08.811.277.656.959.350.718
MeSH Unique ID: D000071449
Registry Number: EC 3.4.21.-
Entry Terms:
- Convertase 9, Proprotein
- Proprotein Convertase, Subtilisin-Kexin Type 9
- Proprotein Convertase, Subtilisin Kexin Type 9
- Neural Apoptosis-Regulated Convertase 1
- Neural Apoptosis Regulated Convertase 1
- NARC-1 Protein
- NARC 1 Protein
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