Death Effector Domain

A homotypic protein interaction module of the death domain superfamily that is composed of a bundle of six alpha-helices. The death effector domain shares sequence and structural similarities with the DEATH DOMAIN and CASPASE RECRUITMENT DOMAIN. It occurs in many proteins with essential functions in APOPTOSIS.

Year introduced: 2017

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): G02.111.570.820.709.275.750.500.395.750

MeSH Unique ID: D000071461

Entry Terms:

• Death Effector Domains
• DED Domain
• DED Domains

Previous Indexing:

• Adaptor Proteins, Signal Transducing (1997-2016)
• Amino Acid Sequence (1997-2016)
• Death Domain Receptor Signaling Adaptor Proteins (2007-2016)

See Also:

• Death Domain Receptor Signaling Adaptor Proteins

All MeSH Categories
Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
Molecular Structure
Molecular Conformation
Protein Conformation
Protein Structural Elements
Protein Domains
Protein Interaction Domains and Motifs
Death Domain Superfamily
Death Effector Domain