AlkB Homolog 8, tRNA Methyltransferase

A dioxygenase and alkylation repair homolog that catalyzes the methylation of 5-carboxymethyl URIDINE to 5-methylcarboxymethyl uridine at the wobble position of the ANTICODON loop in TRANSFER RNA (tRNA) via its methyltransferase domain. It has a preference for tRNA (ARGININE) and tRNA (GLUTAMATE), and does not bind tRNA (LYSINE).

Year introduced: 2017

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Tree Number(s): D08.811.682.690.416.139.984, D08.811.913.555.500.925.500

MeSH Unique ID: D000071503

Registry Number: EC 1.14.11.-

Entry Terms:

• Alkylated DNA Repair Protein Alkb Homolog 8
• Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH8
• Probable Alpha Ketoglutarate Dependent Dioxygenase ABH8
• S-Adenosyl-L-Methionine-Dependent tRNA Methyltransferase ABH8
• S Adenosyl L Methionine Dependent tRNA Methyltransferase ABH8
• tRNA (Carboxymethyluridine(34)-5-O)-Methyltransferase ABH8

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Oxidoreductases
Oxygenases
Dioxygenases
AlkB Enzymes
AlkB Homolog 8, tRNA Methyltransferase

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Transferases
One-Carbon Group Transferases
Methyltransferases
tRNA Methyltransferases
AlkB Homolog 8, tRNA Methyltransferase