Stromal Interaction Molecules
Membrane-associated calcium-binding proteins that are characterized by N-terminal EF HAND MOTIFS and a STERILE ALPHA MOTIF. They function as sensors of ENDOPLASMIC RETICULUM calcium levels and translocate from the ER to the plasma membrane to activate CALCIUM CHANNELS in response to intracellular calcium depletion.
Year introduced: 2017
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Subheadings:
Tree Number(s): D12.776.157.125.806, D12.776.543.875
MeSH Unique ID: D000071736
Entry Terms:
- Stromal Interaction Molecule
- Interaction Molecule, Stromal
- Molecule, Stromal Interaction
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