BTB-POZ Domain

A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC FINGERS or KELCH REPEATS. It is characterized by a tightly intertwined dimer with an extensive hydrophobic interface. A surface-exposed groove lined with conserved amino acids is formed at the dimer interface, suggesting a peptide-binding site. Many BTB proteins are transcriptional regulators that are thought to regulate CHROMATIN structure.

Year introduced: 2017

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Tree Number(s): G02.111.570.820.709.275.750.500.343

MeSH Unique ID: D000071757

Entry Terms:

• BTB POZ Domain
• BTB-POZ Domains
• BTB Domain
• BTB Domains
• POZ Domain
• POZ Domains
• BTB (POZ) Domain
• Broad-Complex, Tramtrack and Bric a Brac Domain
• Broad Complex, Tramtrack and Bric a Brac Domain
• POxvirus and Zinc Finger Domain

Previous Indexing:

• Amino Acid Sequence (1994-2016)
• DNA-Binding Proteins (1994-2016)
• Protein Structure, Tertiary (1995-2016)

All MeSH Categories
Phenomena and Processes Category
Chemical Phenomena
Biochemical Phenomena
Molecular Structure
Molecular Conformation
Protein Conformation
Protein Structural Elements
Protein Domains
Protein Interaction Domains and Motifs
BTB-POZ Domain