Wnt-5a Protein

A Wnt protein and ligand for FRIZZLED RECEPTORS that may function as an inhibitor or activator of the WNT SIGNALING PATHWAY. For example, it activates signaling in the presence of Frizzled-4 but is inhibitory when coupled with ROR2 TYROSINE KINASE. It is required for axis formation during EMBRYOGENESIS and inhibits the proliferation, migration, and invasiveness of cancer cells.

Year introduced: 2017

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Tree Number(s): D12.776.467.984.050, D12.776.624.664.700.962, D23.529.984.050

MeSH Unique ID: D000071818

Entry Terms:

• Wnt 5a Protein
• Wnt5a Protein
• Wingless-Type MMTV Integration Site Family, Member 5A
• Wingless Type MMTV Integration Site Family, Member 5A

Previous Indexing:

• Proto-Oncogene Proteins (1994-2016)
• Wnt Proteins (2006-2016)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Intercellular Signaling Peptides and Proteins
Wnt Proteins
Wnt-5a Protein

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Neoplasm Proteins
Oncogene Proteins
Proto-Oncogene Proteins
Wnt-5a Protein

All MeSH Categories
Chemicals and Drugs Category
Biological Factors
Intercellular Signaling Peptides and Proteins
Wnt Proteins
Wnt-5a Protein