Prion Proteins
Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU.
Year introduced: 2017: for PRION PROTEINS use PRIONS 1991-2016
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Subheadings:
Tree Number(s): D09.400.430.890.448.600, D12.776.395.550.448.600, D12.776.543.484.500.625, D12.776.543.550.418.600, D12.776.785.340
MeSH Unique ID: D000072002
Entry Terms:
- PrP Proteins
- Fatal Familial Insomnia Protein
- Prion Protein
- CD230 Antigen
- Antigen, CD230
- Creutzfeldt-Jakob Disease Protein
- Creutzfeldt Jakob Disease Protein
- Major Prion Protein
- Prion Protein, Major
- Alternative Prion Protein
- Prion Protein, Alternative
- AltPrP
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