Smoothened Receptor
A frizzled-like, G-protein-coupled receptor that associates with PATCHED RECEPTORS to transduce signals from HEDGEHOG PROTEINS and initiate hedgehog signaling to ZINC FINGER PROTEIN GLI1. It may normally inhibit signaling in the absence of SONIC HEDGEHOG PROTEIN binding to PATCHED RECEPTOR-1.
Year introduced: 2017
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Subheadings:
Tree Number(s): D12.776.543.750.695.017.500, D12.776.543.750.850.500.500
MeSH Unique ID: D000072086
Entry Terms:
- Receptor, Smoothened
- Smoothened Receptors
- Receptors, Smoothened
- Smoothened Protein
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