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Ku Autoantigen

An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.

Year introduced: 2017 (1986)

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Subheadings:

Tree Number(s): D08.811.277.040.025.159.155, D08.811.399.340.155, D12.776.157.687.493, D12.776.260.525, D12.776.660.625.625, D12.776.660.720.493, D23.050.290.625

MeSH Unique ID: D000072200

Registry Number: EC 4.2.99.-

Entry Terms:

  • Autoantigen, Ku
  • Ku Antigen
  • Antigen, Ku
  • G22P1 Antigen
  • Antigen, G22P1
  • Ku Heterodimer
  • Heterodimer, Ku
  • Ku Protein
  • Ku70 Antigen
  • Antigen, Ku70
  • XRCC6 Protein
  • X-ray Repair Cross-Complementing Protein 6
  • X ray Repair Cross Complementing Protein 6
  • Ku Autoantigen, 70 kDa
  • Ku80 Antigen
  • Antigen, Ku80
  • XRCC5 Protein
  • X-ray Repair Cross-Complementing Protein 5
  • X ray Repair Cross Complementing Protein 5
  • Ku Autoantigen, 80 kDa

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