Ku Autoantigen
An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.
Year introduced: 2017 (1986)
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Subheadings:
Tree Number(s): D08.811.277.040.025.159.155, D08.811.399.340.155, D12.776.157.687.493, D12.776.260.525, D12.776.660.625.625, D12.776.660.720.493, D23.050.290.625
MeSH Unique ID: D000072200
Registry Number: EC 4.2.99.-
Entry Terms:
- Autoantigen, Ku
- Ku Antigen
- Antigen, Ku
- G22P1 Antigen
- Antigen, G22P1
- Ku Heterodimer
- Heterodimer, Ku
- Ku Protein
- Ku70 Antigen
- Antigen, Ku70
- XRCC6 Protein
- X-ray Repair Cross-Complementing Protein 6
- X ray Repair Cross Complementing Protein 6
- Ku Autoantigen, 70 kDa
- Ku80 Antigen
- Antigen, Ku80
- XRCC5 Protein
- X-ray Repair Cross-Complementing Protein 5
- X ray Repair Cross Complementing Protein 5
- Ku Autoantigen, 80 kDa