Pancreatitis-Associated Proteins
C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker.
Year introduced: 2018 (1992)
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Subheadings:
Tree Number(s): D12.776.503.280.578, D23.050.285.733, D23.101.140.780
MeSH Unique ID: D000073718
Entry Terms:
- Pancreatitis Associated Proteins
- Regenerating Islet-Derived Proteins
- Regenerating Islet Derived Proteins
- Regenerating Islet-Derived Protein
- Islet-Derived Protein, Regenerating
- Protein, Regenerating Islet-Derived
- Regenerating Islet Derived Protein
- Pancreatitis-Associated Protein-1
- Pancreatitis Associated Protein 1
- Pancreatitis-Associated Protein
- Pancreatitis Associated Protein
- Protein, Pancreatitis-Associated
- Regenerating Islet-Derived Protein 3
- Regenerating Islet Derived Protein 3