ATP Binding Cassette Transporter, Subfamily A
A large, highly conserved, subfamily of ATP binding cassette transporters structurally characterized by a membrane-spanning domain composed of six ALPHA-HELICES, a large extracellular loop, nucleotide-binding domain, and a conserved cytoplasmic 80 amino acid sequence. In humans, it includes ABCA1(ATP BINDING CASSETTE TRANSPORTER 1) through ABCA10, as well as ABCA12 and ABCA13.
Year introduced: 2019 (2018)
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Subheadings:
Tree Number(s): D09.400.430.890.020.381, D12.776.157.530.100.050, D12.776.395.550.020.381, D12.776.543.550.192.381, D12.776.543.585.100.190
MeSH Unique ID: D000073874
Entry Terms:
- ATP Binding Cassette Transporter, Sub-Family A
- ATP Binding Cassette Transporter, Sub Family A
- ABCA Transporters
- Transporters, ABCA
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