Zinc Finger E-box Binding Homeobox 2
A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME.
Year introduced: 2018
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Subheadings:
Tree Number(s): D12.776.260.400.883, D12.776.260.703.700, D12.776.930.780.918
MeSH Unique ID: D000074165
Entry Terms:
- Zinc Finger E box Binding Homeobox 2
- Zeb2 Transcription Factor
- Transcription Factor, Zeb2
- Smad-Interacting Protein 1
- Smad Interacting Protein 1
- Zinc Finger E-box Binding Homeobox 2 Protein
- Zinc Finger E box Binding Homeobox 2 Protein
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