Aldo-Keto Reductase Family 1 Member C3

Aldo-keto reductase that functions as a bi-directional 17 BETA, 20 ALPHA-HYDROXYSTEROID DEHYDROGENASE. It catalyzes the reduction of PROSTAGLANDIN D2 and PROSTAGLANDIN H2, as well as the oxidation of 9alpha,11beta-PGF2 to prostaglandin D2. It can also interconvert estrogens, ANDROGENS; and PROGESTINS between their active forms and inactive metabolites.

Year introduced: 2018

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Tree Number(s): D08.811.682.047.150.700.156.875, D08.811.682.047.436.375.140, D08.811.682.047.820.284.937, D08.811.682.047.820.375.500

MeSH Unique ID: D000074425

Registry Number: EC 1.1.1.357

Entry Terms:

• Aldo Keto Reductase Family 1 Member C3
• Dihydrodiol Dehydrogenase 3
• 17-beta-Hydroxysteroid Dehydrogenase Type 5
• 17 beta Hydroxysteroid Dehydrogenase Type 5
• AKR1C3 Protein

Previous Indexing:

• 3-Hydroxysteroid Dehydrogenases (2004-2017)
• Hydroxyprostaglandin Dehydrogenases (2004-2017)

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Oxidoreductases
Alcohol Oxidoreductases
Carbohydrate Dehydrogenases
Sugar Alcohol Dehydrogenases
Aldo-Keto Reductases
Aldo-Keto Reductase Family 1 Member C3

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Oxidoreductases
Alcohol Oxidoreductases
Hydroxysteroid Dehydrogenases
17-Hydroxysteroid Dehydrogenases
Aldo-Keto Reductase Family 1 Member C3

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Oxidoreductases
Alcohol Oxidoreductases
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
Aldo-Keto Reductases
Aldo-Keto Reductase Family 1 Member C3

All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes
Enzymes
Oxidoreductases
Alcohol Oxidoreductases
NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
Hydroxyprostaglandin Dehydrogenases
Aldo-Keto Reductase Family 1 Member C3