AAA Proteins
A large, highly conserved and functionally diverse superfamily of NTPases and nucleotide-binding proteins that are characterized by a conserved 200 to 250 amino acid nucleotide-binding and catalytic domain, the AAA+ module. They assemble into hexameric ring complexes that function in the energy-dependent remodeling of macromolecules. Members include ATPASES ASSOCIATED WITH DIVERSE CELLULAR ACTIVITIES.
Year introduced: 2018
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Subheadings:
Tree Number(s): D08.811.277.040.013, D12.776.157.025
MeSH Unique ID: D000074582
Registry Number: EC 3.6.4.-
Entry Terms:
- AAA Protein
- Protein, AAA
- AAA Superfamily
- Superfamily, AAA
- AAA+ Superfamily
- Superfamily, AAA+
- P-Loop NTPases
- NTPases, P-Loop
- P Loop NTPases
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