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Abuse-Deterrent Formulations

Drug formulations or delivery systems intended to discourage the abuse of CONTROLLED SUBSTANCES. These may include physical barriers to prevent chewing or crushing the drug; chemical barriers that prevent extraction of psychoactive ingredients; agonist-antagonist combinations to reduce euphoria associated with abuse; aversion, where controlled substances are combined with others that will produce an unpleasant effect if the patient manipulates the dosage form or exceeds the recommended dose; delivery systems that are resistant to abuse such as implants; or combinations of these methods.

Year introduced: 2018

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Subheadings:

Tree Number(s): D26.255.075, D27.505.696.034, D27.505.696.663.850.007, D27.505.954.427.005, E02.319.300.127, E05.916.250.500

MeSH Unique ID: D000075162

Entry Terms:

  • Abuse Deterrent Formulations
  • Abuse-Deterrent Formulation
  • Abuse Deterrent Formulation
  • Formulation, Abuse-Deterrent
  • Formulations, Abuse-Deterrent

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