Anoctamins
A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding.
Year introduced: 2018
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Subheadings:
Tree Number(s): D12.776.157.530.400.175.032, D12.776.543.550.450.175.032, D12.776.543.585.400.175.032
MeSH Unique ID: D000075368
Entry Terms:
- TMEM16 Proteins
- Anoctamin
- TMEM16 Protein Family
- Protein Family, TMEM16
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