Cell Adhesion Molecule-1
A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.
Year introduced: 2018
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Tree Number(s): D09.400.430.890.200.115, D12.776.395.550.200.115, D12.776.543.550.200.128, D23.050.301.350.115
MeSH Unique ID: D000075982
Entry Terms:
- Adhesion Molecule-1, Cell
- Cell Adhesion Molecule 1
- Molecule-1, Cell Adhesion
- CADM1 Protein
- IGSF4 Protein
- TSLC1 Protein
- Tumor Suppressor in Lung Cancer 1 Protein
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