Disks Large Homolog 4 Protein
A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY.
Year introduced: 2018
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Tree Number(s): D08.811.913.696.650.450.750, D12.644.360.265, D12.776.476.265, D12.776.543.219, D12.776.631.224
MeSH Unique ID: D000076122
Entry Terms:
- Synapse-Associated Protein 90
- Synapse Associated Protein 90
- Postsynaptic Density Protein 95
- SAP90 Protein
- SAP-90 Protein
- SAP 90 Protein
- PSD95 Protein
- Discs Large Homolog 4 Protein
- PSD-95 Protein
- PSD 95 Protein
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