Myristoylated Alanine-Rich C Kinase Substrate
A membrane and ACTIN CYTOSKELETON associated, N-terminal myristoylated protein that binds CALMODULIN and is a prominent substrate for PROTEIN KINASE C. Both phosphorylation and poly(ADP)-ribosylation inhibit its F-ACTIN crosslinking activity; phosphorylation also causes MARCKS to relocate from the membrane to cytoplasm.
Year introduced: 2018 (1989)
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Subheadings:
Tree Number(s): D05.750.078.730.556, D12.644.360.537, D12.776.157.142.375, D12.776.157.687.496, D12.776.220.525.556, D12.776.476.539, D12.776.543.637, D12.776.660.720.496
MeSH Unique ID: D000076250
Registry Number: 125267-21-2
Entry Terms:
- Myristoylated Alanine Rich C Kinase Substrate
- MARCKS Protein
- ACAMP-81