Decitabine
An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.
Year introduced: 2019 (1977)
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Subheadings:
Tree Number(s): D02.145.150.500, D03.383.742.680.245.217.500, D13.570.685.245.217.500, D13.570.800.286.300.500
MeSH Unique ID: D000077209
Registry Number: 776B62CQ27
Entry Terms:
- 5-Azadeoxycytidine
- 5 Azadeoxycytidine
- AzadC Compound
- Compound, AzadC
- 5-Aza-2'-deoxycytidine
- 5 Aza 2' deoxycytidine
- 5-AzadC
- 2'-Deoxy-5-azacytidine
- 2' Deoxy 5 azacytidine
- 5AzadC
- NSC 127716
- NSC-127716
- NSC127716
- Dacogen
- Decitabine Mesylate
- Mesylate, Decitabine
- 5-Deoxyazacytidine
- 5 Deoxyazacytidine
See Also:
Pharmacologic Action: