Aprepitant

A morpholine neurokinin-1 (NK1) receptor antagonist that is used in the management of nausea and vomiting caused by DRUG THERAPY, and for the prevention of POSTOPERATIVE NAUSEA AND VOMITING.

Year introduced: 2019 (1998)

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D03.383.533.640.125

MeSH Unique ID: D000077608

Registry Number: 1NF15YR6UY

Entry Terms:

• (1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(fluoro)phenyl-4-(3-oxo-1,2,4-triazol-5-yl)methylmorpholine
• L 754030
• L 754,030
• L-754,030
• L754,030
• L-754030
• L754030
• MK 869
• MK-869
• MK869
• MK-0869
• MK0869
• MK 0869
• Emend
• MK 0517
• MK-0517
• MK0517
• (2R)-(1R)-3,5-bis(Trifluoromethylphenyl)ethoxy)-(3S)-(4-fluoro)phenyl-4-(3-(5-oxo-1H,4H-1,2,4-triazole)methyl-morpholine

Pharmacologic Action:

• Antiemetics
• Neurokinin-1 Receptor Antagonists

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Oxazines
Morpholines
Aprepitant