Protein-Arginine Deiminase Type 1
A peptidylarginine deiminase isoenzyme. It is a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner. It functions within the epidermis, targeting INTERMEDIATE FILAMENTS; KERATINS; and filaggrin for CITRULLINATION to promote epidermal cornification.
Year introduced: 2020 (1999)
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Subheadings:
Tree Number(s): D08.811.277.721.250
MeSH Unique ID: D000080062
Registry Number: EC 3.5.3.15
Entry Terms:
- Peptidylarginine Deiminase Type I
- PAD Type I
- Peptidyl Arginine Deiminase Type 1
- Peptidyl Arginine Deiminase Type I
- Protein Arginine Deiminase Type 1
- Protein Arginine Deiminase Type I
- Protein-Arginine Deiminase Type I
- Peptidylarginine Deiminase I
- Protein Arginine Deiminase 1
- PADI1 Protein
- Peptidylarginine Deiminase Type 1
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