Hydrogen Deuterium Exchange-Mass Spectrometry

A mass spectrometry method utilizing hydrogen-deuterium exchange kinetics to study conformational and dynamic changes especially of proteins, such as interactions during ligand binding and allosteric effects during catalysis.

Year introduced: 2020

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Tree Number(s): E05.196.344.500, E05.196.566.550

MeSH Unique ID: D000080307

Entry Terms:

• Hydrogen Deuterium Exchange Mass Spectrometry
• H-D Exchange Mass Spectrometry
• H D Exchange Mass Spectrometry
• HDX-MS
• HDX MS

Previous Indexing:

• Deuterium Exchange Measurement (2003-2019)

All MeSH Categories
Analytical, Diagnostic and Therapeutic Techniques and Equipment Category
Investigative Techniques
Chemistry Techniques, Analytical
Deuterium Exchange Measurement
Hydrogen Deuterium Exchange-Mass Spectrometry

All MeSH Categories
Analytical, Diagnostic and Therapeutic Techniques and Equipment Category
Investigative Techniques
Chemistry Techniques, Analytical
Mass Spectrometry
Hydrogen Deuterium Exchange-Mass Spectrometry