Shelterin Complex
A TELOMERE cap complex consisting of telomere-specific proteins in association with telomeric DNA such as telomeric dsDNA-sDNA junction. They are involved in the protection of chromosome ends and TELOMERASE regulation and play a role in CELLULAR SENESCENCE and ageing-related pathology. In general it consists of six mostly TELOMERE-BINDING PROTEINS (POT1, RAP1, TIN2, TPP1, TRF1, and TRF2).
Year introduced: 2022
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Subheadings:
Tree Number(s): A11.284.430.106.279.345.190.160.845.500, D05.500.918, D12.776.260.735.625, D12.776.660.235.700.625, D12.776.664.981, G05.360.160.845.500
MeSH Unique ID: D000089804
Entry Terms:
- Complex, Shelterin
- Telomere POT1-TPP1 Complex
- Complex, Telomere POT1-TPP1
- POT1-TPP1 Complex, Telomere
- Telomere POT1 TPP1 Complex
- Telosome
- Telosomes
- POT1-TPP1 Shelterin Complex
- Complex, POT1-TPP1 Shelterin
- POT1 TPP1 Shelterin Complex
- Shelterin Complex, POT1-TPP1
- CST Complex
- Complex, CST
- Ctc1-Stn1-Ten1 Complex
- Complex, Ctc1-Stn1-Ten1
- Ctc1 Stn1 Ten1 Complex
- Telomeric Capping Complex
- Capping Complex, Telomeric
- Complex, Telomeric Capping
- Telomeric Stn1-Ten1 Capping Complex
- Telomeric Stn1 Ten1 Capping Complex
- Telomere Cap Complex
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