RNA, Guide, CRISPR-Cas Systems

A component of CRISPR-Cas SYSTEMS. Cas endodeoxyribonucleases assemble with a guide RNA complex, a hybrid of CRISPR RNA (crRNA) and transactivating crRNA (tracrRNA) molecules, to form an active complex that cleaves DNA. crRNA and tracrRNA can be synthetically fused into a single RNA molecule, namely single guide RNA. Synthetic sgRNA is used with CRISPR-Cas SYSTEMS for targeted GENE EDITING.

Year introduced: 2023

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Tree Number(s): D13.444.735.790.552.563

MeSH Unique ID: D000094704

Entry Terms:

• RNA, Guide (CRISPR-Cas Systems)
• Guide RNA, CRISPR-Cas Systems
• Guide RNA, CRISPR Cas Systems
• Guide RNA (CRISPR-Cas Systems)
• RNA, CRISPR Guide
• Guide RNA, CRISPR
• crRNA
• CRISPR Guide RNA
• RNA, Single Guide
• Guide RNA, Single
• sgRNA (Single-Guide RNA)
• CRISPR-Cas Systems sgRNA (Single Guide RNA)
• sgRNA (CRISPR-Cas Systems)
• RNA, Single-Guide
• Single Guide RNA
• Single-Guide RNA
• crRNA, Transactivating
• Transactivating crRNA
• tracrRNA

Previous Indexing:

• CRISPR-Cas Systems (2014-2022)
• RNA, Guide, CRISPR-Cas Systems (2008-2022)

See Also:

• CRISPR-Cas Systems

All MeSH Categories
Chemicals and Drugs Category
Nucleic Acids, Nucleotides, and Nucleosides
Nucleic Acids
RNA
RNA, Untranslated
RNA, Small Untranslated
RNA, Guide, CRISPR-Cas Systems