Calponins
A family of actin binding proteins mostly in smooth muscle. Calponins include most abundant alpha-calponin (h1 or basic); beta-calponin; neutral calponin (h2 calponin); acidic calponin, SM22, and transgelin. Calponin family members have N-terminal single Calponin Homology (CH) domain and multiple C-terminus 23-amino acids long calponin-like repeats called CLICK-23. Calponins participate in modulation of smooth muscle contraction by binding to ACTINS (F- and G-Actins), CALMODULIN and TROPOMYSIN.
Year introduced: 2024
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Subheadings:
Tree Number(s): D05.750.078.730.266, D12.776.157.125.123, D12.776.210.500.187, D12.776.220.525.268
MeSH Unique ID: D000096985
Entry Terms:
- Calponin
- Calponin Family Proteins
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