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HLA-E Antigens

Class I human histocompatibility (HLA) antigens encoded by genes at the E locus on chromosome 6. They bind a restricted subset of peptides derived from the leader peptides of other class I molecules. They primarily are involved with down-regulating cytolytic activity of NK CELLS and restricting non-canonical CD8-POSITIVE T LYMPHOCYTES.

Year introduced: 2024 (1988)

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Subheadings:

Tree Number(s): D09.400.430.890.489.850, D12.776.395.550.489.850, D12.776.543.550.439.850, D23.050.301.500.100.850, D23.050.705.552.100.850

MeSH Unique ID: D000097625

Entry Terms:

  • HLA E Antigens
  • HLA-E*01:03 antigen
  • HLA-E 0103 antigen
  • HLA-E*0103
  • HLA-E*01:01 antigen
  • HLA-E*0101 antigen
  • HLA E*0101 antigen

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