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Calcimycin

An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.

Year introduced: 1991(1975)

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Tree Number(s): D02.355.291.933.125, D02.540.576.625.125, D03.633.100.221.173, D04.345.241.654.125, D04.345.674.625.125

MeSH Unique ID: D000001

Registry Number: 37H9VM9WZL

Entry Terms:

  • 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, (6S-(6alpha(2S*,3S*),8beta(R*),9beta,11alpha))-
  • A-23187
  • A 23187
  • Antibiotic A23187
  • A23187, Antibiotic
  • A23187

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