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Angiotensin II

An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.

Year introduced: 1974(1963)

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Subheadings:

Tree Number(s): D06.472.699.094.078, D12.644.400.070.078, D12.644.456.073.041, D12.644.548.058.078, D12.776.631.650.070.078, D23.469.050.050.050

MeSH Unique ID: D000804

Registry Number: 11128-99-7

Entry Terms:

  • Angiotensin-(1-8) Octapeptide
  • ANG-(1-8)Octapeptide
  • Angiotensin II, Val(5)-
  • Angiotensin II, Valine(5)-
  • Valyl(5)-Angiotensin II
  • Angiotensin II, Ile(5)-
  • 5-L-Isoleucine Angiotensin II
  • 5 L Isoleucine Angiotensin II
  • Angiotensin II, 5-L-Isoleucine
  • Isoleucyl(5)-Angiotensin II
  • Angiotensin II, Isoleucine(5)-
  • Isoleucine(5)-Angiotensin

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Pharmacologic Action:

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