Antibody Affinity

A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of avidity, which refers to the strength of the antigen-antibody bond after formation of reversible complexes.

Year introduced: 1979

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): G12.040, G12.122.125

MeSH Unique ID: D000915

Entry Terms: