Arachidonate 12-Lipoxygenase
An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in PLATELETS.
Year introduced: 1991(1987)
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Subheadings:
Tree Number(s): D08.811.682.690.416.583.500.060, D12.776.556.579.374.568.500.025
MeSH Unique ID: D001092
Registry Number: EC 1.13.11.31
Entry Terms:
- 12-Lipoxygenase, Arachidonate
- Arachidonate 12 Lipoxygenase
- 12-Lipoxygenase
- 12 Lipoxygenase
- Arachidonic Acid 12-Lipoxygenase
- 12-Lipoxygenase, Arachidonic Acid
- Arachidonic Acid 12 Lipoxygenase
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