Basement Membrane

A darkly stained mat-like EXTRACELLULAR MATRIX (ECM) that separates cell layers, such as EPITHELIUM from ENDOTHELIUM or a layer of CONNECTIVE TISSUE. The ECM layer that supports an overlying EPITHELIUM or ENDOTHELIUM is called basal lamina. Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN; glycoprotein LAMININ; and PROTEOGLYCAN, provides barriers as well as channels between interacting cell layers.

Year introduced: 1967(1965)

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Tree Number(s): A10.615.179, A11.284.295.310.070

MeSH Unique ID: D001485

Entry Terms:

• Basement Membranes
• Membrane, Basement
• Membranes, Basement
• Basal Lamina
• Lamina, Basal
• Basement Lamina
• Lamina, Basement
• Lamina Lucida
• Lucida, Lamina
• Lamina Densa
• Densas, Lamina
• Lamina Reticularis
• Reticularis, Lamina

All MeSH Categories
Anatomy Category
Tissues
Membranes
Basement Membrane
Basilar Membrane
Bruch Membrane
Descemet Membrane
Glomerular Basement Membrane

All MeSH Categories
Anatomy Category
Cells
Cellular Structures
Extracellular Space
Extracellular Matrix
Basement Membrane