3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester

A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.

Year introduced: 1987

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Tree Number(s): D03.383.725.203.600, D03.383.725.547.900

MeSH Unique ID: D001498

Registry Number: 71145-03-4

Entry Terms:

• Bay-R-5417
• BayR5417
• Bay R 5417
• Bay R5417
• R5417, Bay
• Bay-K-8644, (+-)-Isomer
• Bay-K-8644, (-)-Isomer
• Bay-K-8644, (+)-Isomer
• Bay-K-8644
• BayK8644
• Bay K 8644
• BK-8644
• BK8644
• BK 8644
• Bay-K8644
• Bay K8644

Previous Indexing:

• Nifedipine/analogs and derivatives (1975-1986)
• Pyridines (1966-1974)

Pharmacologic Action:

• Calcium Channel Agonists

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Pyridines
Dihydropyridines
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Pyridines
Nicotinic Acids
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester