Buprenorphine
A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
Year introduced: 1987(1979)
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Tree Number(s): D03.132.577.249.150, D03.605.497.150, D03.633.400.686.150, D04.615.723.795.150
MeSH Unique ID: D002047
Registry Number: 40D3SCR4GZ
Entry Terms:
- Subutex
- Temgésic
- Buprex
- Temgesic
- Buprenorphine Hydrochloride
- Hydrochloride, Buprenorphine
- 6029-M
- 6029M
- 6029 M
- RX-6029-M
- RX6029M
- RX 6029 M
- Buprenex
- Prefin
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