Busulfan

An alkylating agent having a selective immunosuppressive effect on BONE MARROW. It has been used in the palliative treatment of chronic myeloid leukemia (MYELOID LEUKEMIA, CHRONIC), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.

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Tree Number(s): D02.033.455.125.125, D02.455.326.146.100.050.500.100, D02.886.645.600.055.050.510.100

MeSH Unique ID: D002066

Registry Number: G1LN9045DK

Entry Terms:

• Busulphan
• n-Butane-1,3-di(methylsulfonate)
• Myleran
• Myléran
• Mylecytan
• Myelosan
• Glyzophrol
• Busulfan Wellcome
• Wellcome, Busulfan
• Busulfex

Pharmacologic Action:

• Alkylating Agents
• Immunosuppressive Agents
• Antineoplastic Agents, Alkylating
• Myeloablative Agonists

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Alcohols
Glycols
Butylene Glycols
Busulfan

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Hydrocarbons
Hydrocarbons, Acyclic
Alkanes
Alkanesulfonic Acids
Alkanesulfonates
Mesylates
Busulfan

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Sulfur Compounds
Sulfur Acids
Sulfonic Acids
Alkanesulfonic Acids
Alkanesulfonates
Mesylates
Busulfan