Caffeine

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.

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Tree Number(s): D03.132.960.175, D03.633.100.759.758.824.175

MeSH Unique ID: D002110

Registry Number: 3G6A5W338E

Entry Terms:

• 1,3,7-Trimethylxanthine
• No Doz
• Caffedrine
• Coffeinum N
• Coffeinum Purrum
• Dexitac
• Durvitan
• Percoffedrinol N
• Vivarin
• Percutaféine
• Quick-Pep
• QuickPep
• Quick Pep

Pharmacologic Action:

• Central Nervous System Stimulants
• Phosphodiesterase Inhibitors
• Purinergic P1 Receptor Antagonists

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Alkaloids
Xanthines
Caffeine

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, Fused-Ring
Heterocyclic Compounds, 2-Ring
Purines
Purinones
Xanthines
Caffeine