Cimetidine

A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.

Year introduced: 1984(1978)

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Tree Number(s): D02.078.370.200, D03.383.129.308.130

MeSH Unique ID: D002927

Registry Number: 80061L1WGD

Entry Terms:

• N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine
• Altramet
• Biomet
• Biomet400
• Tagamet
• SK and F-92334
• SK and F92334
• SK and F 92334
• SKF-92334
• SKF92334
• SKF 92334
• Histodil
• Eureceptor
• Cimetidine Hydrochloride
• Hydrochloride, Cimetidine
• Cimetidine HCl
• HCl, Cimetidine

Previous Indexing:

• Guanidines (1966-1977)
• Imidazoles (1966-1977)

Pharmacologic Action:

• Anti-Ulcer Agents
• Histamine H2 Antagonists
• Cytochrome P-450 CYP1A2 Inhibitors

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Amidines
Guanidines
Cimetidine

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Azoles
Imidazoles
Cimetidine