Complement C2

A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).

Year introduced: 2006 (1975)

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Tree Number(s): D12.776.124.486.274.150

MeSH Unique ID: D003175

Entry Terms:

• C2, Complement
• C2 Complement
• Complement, C2
• Complement 2
• Complement Component 2
• Component 2, Complement

Previous Indexing:

• Complement (1968-1974)
• Magnesium (1966-1974)
• Protein Binding (1966-1974)

Pharmacologic Action:

• Immunologic Factors

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Blood Proteins
Immunoproteins
Complement System Proteins
Complement C2
Complement C2a
Complement C2b