Cyclosporins

A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.

Year introduced: 1982

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Tree Number(s): D04.345.566.235, D12.644.641.235

MeSH Unique ID: D003524

Entry Terms:

• Cyclosporines

Previous Indexing:

• Immunosuppressive Agents (1966-1981)
• Peptides (1966-1970)
• Peptides, Cyclic (1971-1981)

Pharmacologic Action:

• Enzyme Inhibitors
• Immunosuppressive Agents

All MeSH Categories
Chemicals and Drugs Category
Polycyclic Compounds
Macrocyclic Compounds
Peptides, Cyclic
Cyclosporins
Cyclosporine

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Peptides
Peptides, Cyclic
Cyclosporins
Cyclosporine