De Lange Syndrome

A syndrome characterized by growth retardation, severe MENTAL RETARDATION, short stature, a low-pitched growling cry, brachycephaly, low-set ears, webbed neck, carp mouth, depressed nasal bridge, bushy eyebrows meeting at the midline, hirsutism, and malformations of the hands. The condition may occur sporadically or be associated with an autosomal dominant pattern of inheritance or duplication of the long arm of chromosome 3. (Menkes, Textbook of Child Neurology, 5th ed, p231)

Year introduced: 2000(1964)

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): C10.597.606.360.210, C16.131.077.272, C16.131.260.210, C16.320.180.210

MeSH Unique ID: D003635

Entry Terms:

• Cornelia De Lange Syndrome
• Brachmann-De Lange Syndrome
• Brachmann De Lange Syndrome
• Syndrome, Brachmann-De Lange
• Typus Degenerativus Amstelodamensis
• Amstelodamensis, Typus Degenerativus
• De Lange's Syndrome
• Cornelia de Lange Syndrome 2
• CdLS, X-Linked
• CdLS, X Linked
• CdLSs, X-Linked
• X-Linked CdLS
• X-Linked CdLSs
• CdLS2
• Cornelia de Lange Syndrome, X-Linked
• Cornelia de Lange Syndrome, X Linked
• Cornelia de Lange Syndrome 3
• Cornelia de Lange Syndrome 1

See Also:

• Intellectual Disability

All MeSH Categories
Diseases Category
Nervous System Diseases
Neurologic Manifestations
Neurobehavioral Manifestations
Intellectual Disability
De Lange Syndrome

All MeSH Categories
Diseases Category
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Congenital Abnormalities
Abnormalities, Multiple
De Lange Syndrome

All MeSH Categories
Diseases Category
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Congenital Abnormalities
Chromosome Disorders
De Lange Syndrome

All MeSH Categories
Diseases Category
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Genetic Diseases, Inborn
Chromosome Disorders
De Lange Syndrome