Fibrinogen
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
PubMed search builder options
Subheadings:
Tree Number(s): D12.776.124.050.250, D12.776.124.125.500, D12.776.811.300, D23.119.490
MeSH Unique ID: D005340
Registry Number: 9001-32-5
Entry Terms:
- Coagulation Factor I
- Factor I, Coagulation
- Factor I
- Blood Coagulation Factor I
- gamma-Fibrinogen
- gamma Fibrinogen
See Also: