Flunarizine

Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.

Year introduced: 1987

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Tree Number(s): D03.383.606.450

MeSH Unique ID: D005444

Registry Number: R7PLA2DM0J

Entry Terms:

• Flunarizin
• Sibelium
• R-14950
• R14950
• R 14950
• Flunarizine Hydrochloride
• Hydrochloride, Flunarizine
• Flunarizine Dihydrochloride
• Dihydrochloride, Flunarizine

Previous Indexing:

• Cinnarizine/analogs and derivatives (1975-1986)
• Piperazines (1966-1974)

Pharmacologic Action:

• Anticonvulsants
• Calcium Channel Blockers
• Histamine H1 Antagonists
• Vasodilator Agents

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Piperazines
Flunarizine